Anaerobic Degradation ofN-ε-Carboxymethyllysine, a Major Glycation End-Product, by Human Intestinal Bacteria
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چکیده
منابع مشابه
A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer
Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function. The resulting modifications induce inflammation by binding to scavenger receptors. An increase in advanced glycation end products is observed in a number of diseases e.g. atherosclerosi...
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Effects of carboxymethyllysine (CML), an advanced glycation end-product (AGE), at 1, 2, 4, 8 or 16 μmol/l upon invasion and migration of A549 cells, non-small cell lung cancer (NSCLC) cells, were investigated. Results showed that CML at used test doses did not affect A549 cell growth. However, CML at 4-16 μmol/l enhanced both invasion and migration, and stimulated the release of reactive oxygen...
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ژورنال
عنوان ژورنال: Journal of Agricultural and Food Chemistry
سال: 2019
ISSN: 0021-8561,1520-5118
DOI: 10.1021/acs.jafc.9b02208